Kinesiology Ph. D Student, Edwin Miranda

The University of Michigan, School of Kinesiology is proud to have Edwin Miranda as one of its Ph. D students. Together with five other top research scientists, Edwin Miranda wrote a paper on how metabolic and inflammatory diseases such as atherosclerosis and diabetes are induced by a diet that is rich in fats; the National Institute of Health partly funded this paper. It proved the theory of eating a fat-rich diet can cause a lot of cardiac-related diseases to the person that is engaging in this lifestyle.

Edwin Miranda and his team found out that RAGE (The receptor for advanced glycation end products) when it comes to the pathophysiology of metabolic diseases, plays significant part of ensuring that these effects are stifled (this is achieved together with its receptor that is in soluble form (sRAGE)). The scientists’ objective was to find out the consequences of a meal that is rich in fats consumed by a person who has just exercised and one who has not. They got volunteers who were able to eat the meals after they had done some severe aerobic workouts but after they had consumed it earlier without having exercised.

The conclusion to this successful research that was done by Edwin Miranda and his team with 12 volunteers proved to be quite fascinating. It was found that RAGE had not many effects on when the volunteers did the exercise versus when they did not. The processes that are stifled by RAGE are otherwise unaffected as the study concluded although more research needs to be done to show how RAGE and a High-Fat Meal are correlated. This paper showed that the Ph. D student at the School of Kinesiology at the University of Michigan is not only a brilliant scientist but also an excellent team member as the study suggests.

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